PLATELET-RICH FIBRIN
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WHAT IT IS
Platelet-rich fibrin, or PRF, is prepared from a small sample of your own blood. After processing, the resulting platelet- and fibrin-containing concentrate can be applied topically following microneedling or prepared as PRF EZGEL, an injectable gel used for subtle soft-tissue enhancement.
Because PRF is autologous, it is derived from your own blood rather than a manufactured filler material. Treatment is individualized based on your anatomy, skin quality, goals, and medical history.
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HOW IT WORKS
PRF + microneedling
During microneedling, controlled microchannels are created in the skin as part of a treatment designed to support gradual improvement in the appearance of skin texture and overall quality.
PRF may be applied topically during or immediately after microneedling. The fibrin matrix may help retain platelets and signaling proteins at the treatment site; however, the clinical evidence for PRF as a topical microneedling adjunct is still evolving, and outcomes vary.
PRF EZGEL
PRF EZGEL is prepared from your own blood using a specialized processing method that creates a soft, malleable gel. It may be placed in carefully selected areas to provide subtle support, contour, or volume.
EZGEL is not the same as a hyaluronic acid dermal filler, and it should not be expected to produce the same degree, duration, or predictability of volume enhancement.
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WHAT TO EXPECT
A small blood sample is collected and processed in the studio. The treatment selected—topical PRF with microneedling, injectable PRF, or PRF EZGEL—will depend on your goals and the areas being treated.
Microneedling may cause temporary redness, warmth, tightness, swelling, tenderness, or pinpoint bleeding. Injectable treatment may cause temporary swelling, bruising, tenderness, or asymmetry. Results are gradual and variable. Some patients may require a series of treatments, and no specific outcome can be guaranteed.
FAQs
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With PRF microneedling, PRF is applied topically as an adjunct to a microneedling treatment. With PRF EZGEL, the processed PRF is prepared into a gel and injected into selected areas for subtle soft-tissue support or volume.
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No. PRF is made from your own blood and does not have the same composition, behavior, or predictable volume effect as an FDA-approved hyaluronic acid dermal filler. PRF EZGEL may provide some temporary volume or contouring, but results are generally more subtle and variable.
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PRF contains platelets and fibrin, which are involved in the body’s normal wound-healing processes. PRF is proposed to support tissue remodeling, but individual response varies and the evidence for cosmetic applications remains developing. We do not guarantee collagen production or a specific result.
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Potential treatment areas may include the face, under-eye region, cheeks, acne-scarred areas, neck, or other areas determined appropriate during consultation. Not every area is appropriate for every treatment.
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Microneedling may cause warmth, pressure, or a prickling sensation. A topical anesthetic may be used when appropriate. Injectable treatment involves needle or cannula placement and may cause temporary discomfort, tenderness, swelling, or bruising.
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Downtime varies by treatment. After microneedling, redness and sensitivity may last approximately one to several days. Injectable treatment may involve swelling or bruising that can last several days or longer. Your clinician will provide individualized aftercare instructions.
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The number of treatments depends on your goals, baseline skin condition, treatment area, and response. Some patients choose a single treatment, while others may benefit from a series. A treatment plan will be discussed during consultation.
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The duration and visibility of results vary considerably. PRF microneedling results develop gradually, while PRF EZGEL may provide temporary soft-tissue support. Longevity depends on the treatment area, the amount used, individual metabolism, and other factors.
CONTACT US: Explore platelet-rich fibrin treatments at 27 Skin Studio in Costa Mesa. Schedule a consultation to determine whether topical PRF with microneedling, injectable PRF, or PRF EZGEL is appropriate for your goals.
DISCLAIMER: PRF treatments use a patient’s own blood and are individualized medical procedures. Information on this page is for general educational purposes and does not guarantee a particular result. The benefits, limitations, risks, alternatives, and expected recovery will be reviewed during consultation. Treatment may be performed only when determined medically appropriate by a qualified healthcare professional.